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Seddon, Dr Beatrice beatrice.seddon**[ta]**h.nhs.uk

CRUK/14/015: IMRiS - A phase II study of intensity modulated radiotherapy (IMRT) in primary bone and soft tissue sarcoma University College London 01/01/2015 31/12/2020 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Seymour, Professor Leonard len.seymour**[ta]**ology.ox.ac.uk

Potentiating Oncolytic Virotherapy by Cancer-Selective Expression of Biologics University of Oxford 01/10/2014 30/09/2019 Science Committee - Programme Award Science Committee

Seymour, Professor Matthew m.seymour**[ta]**n.org.uk

EORTC Liaison Ofcer Post (co-funded) University of Leeds 01/09/2013 31/08/2016 Clinical and Translational Research Committee - Clinical Trials Unit - Programme Award Clinical Trials Awards & Advisory Committee

CRUK/12/022: Alternative chemotherapy for frailer patients with advanced gastric or oesophageal cancer (GO-2) University of Leeds 01/04/2013 30/06/2018 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Shankar, Dr Ananth CRUK/10/039: EuroNet PHL-LP1 University of Birmingham 01/10/2011 30/09/2017 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Sharma, Dr Ricky ricky.sharma**[ta]**ology.ox.ac.uk

CRUK/07/030: FOXFIRE: Randomised phase II-III trial of 5-Fluorouracil, Oxaliplatin, Folinic acid +/- Interventional Radio-Embolisation with yttrium-90 SIR-Spheres in metastatic colorectal cancer (supported by the Bobby Moore fund) University of Oxford 01/03/2008 31/10/2016 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Sharrocks, Professor Andrew a.d.sharrocks**[ta]**chester.ac.uk

Transcriptional control mechanisms of immediateearly genes: the convergence of phosphorylation, acetylation, parylation and sumoylation regulatory events University of Manchester 01/09/2011 31/10/2015 Biological Sciences Committee - Project Award Science Committee

Shaw, Professor Jacqueline js39**[ta]**cester.ac.uk

Towards personalised cancer care: circulating nucleic acids for early detection and monitoring of breast cancer University of Leicester 01/03/2012 28/02/2017 Clinical and Translational Research Committee - Programme Award Science Committee

Shaw, Professor Richard richard.shaw**[ta]**erpool.ac.uk

CRUK/08/014: HOPON (Hyperbaric Oxygen for the Prevention of Osteoradionecrosis): A Randomised Controlled Trial of Hyperbaric Oxygen to prevent Osteoradionecrosis of the Irradiated Mandible (supported by Stand Up To Cancer) University of Liverpool 01/06/2010 31/05/2018 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory CommitteeCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.CRUK/11/042: DAHANCA 21: Hyperbaric Oxygen Treatment of Mandibular Osteoradionecrosis.A randomised clinical trial.University of Liverpool 01/01/2013 31/12/2016 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Short, Professor Susan s.c.short**[ta]**ds.ac.uk

CRUK/11/057: A randomised phase 2 trial investigating the additional beneft of hydroxychloroquine to short course radiotherapy in patients aged 70 years and older with high grade gliomas.A sub study investigating the role of 18 F FDG PET CT in addition to MRI in detecting tumour response University College London 01/01/2013 31/12/2015 Clinical Trials Awards & Advisory Committee - Feasibility Study Clinical Trials Awards & Advisory Committee

Sibson, Professor Nicola nicola.sibson**[ta]**ology.ox.ac.uk

Role of the inflammatory and metabolic microenvironment in brain metastasis: imaging biomarkers and the impact of radiotherapy Cancer Research UK/ MRC Oxford Institute for Radiation Oncology 01/05/2013 30/04/2018 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Siebold, Dr Christian Molecular mechanisms of cell-surface morphogen signalling University of Oxford 01/10/2012 30/09/2018 New Investigator Committee - Senior Cancer Research Fellowship New Investigator Committee

Molecular mechanisms of cell-surface morphogen signalling University of Oxford 01/10/2014 30/09/2018 New Investigator Committee - Studentship New Investigator Committee

Sieger, Dr Dirk dirk.sieger**[ta]**ac.uk

In vivo studies of microglia-glioma interactions University of Edinburgh 01/11/2014 31/10/2020 New Investigator Committee - Career Establishment Award New Investigator Committee

Slevin, Professor Nicholas nick.slevin**[ta]**istie.nhs.uk

CRUK/13/006: NIMRAD - A randomised placebocontrolled trial of synchronous NIMorazole versus RADiotherapy alone in patients with locally advanced head and neck squamous cell carcinoma not suitable for synchronous chemotherapy or cetuximab (supported by Stand Up To Cancer) University of Manchester 01/09/2013 29/02/2020 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Smalley, Dr Matthew SmalleyMJ**[ta]**diff.ac.uk

Stem and progenitor cells and the origins of breast cancer heterogeneity Cardiff University 01/05/2013 30/04/2018 Science Committee - Programme Award Science Committee

Smith, Dr Katherine katherine.smith**[ta]**ac.uk

Scottish Public Health Supplement case study University of Edinburgh 01/04/2015 31/12/2015 Tobacco Advisory Group - Commissioned Research Tobacco Advisory Group

Smith, Dr Matthew CRUK/08/040: MARALL - Phase 2 study combining humanised anti-CD20 (Veltuzumab), anti-CD22 (Epratuzumab) or both monoclonal antibodies with intensive chemotherapy in adults with recurrent acute lymphoblastic leukaemia (ALL) Queen Mary, University of London 01/11/2008 31/08/2016 Clinical Trials Awards & Advisory Committee - Feasibility Study Clinical Trials Awards & Advisory Committee

Smith, Dr Samuel sam.smith**[ta]**l.ac.uk

Mapping Incorrect Causal Beliefs About Cancer: The IBAC study Queen Mary, University of London 01/04/2015 31/03/2016 Population Research Committee - BUPA Foundation Fund - Innovation Grant Population Research CommitteeCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.Poison or prevention: do cognitive representations of breast cancer chemoprevention affect adherence Queen Mary, University of London 01/10/2014 30/09/2017 Population Research Committee - Postdoctoral Fellowship Population Research Committee

So, Professor Chi Wai Eric Characterization of origin-specifc leukaemic stem cells King's College London 01/02/2014 31/01/2019 Science Committee - Programme Award Science Committee

Somervaille, Dr Tim tim.somervaille**[ta]**k.manchester.ac.uk

Leukaemia Biology Group University of Manchester 01/01/2014 31/12/2018 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Sousa-Nunes, Dr Rita Mechanisms of neural tumourigenesis.King's College London 01/10/2012 30/09/2018 New Investigator Committee - Career Development Fellowship New Investigator Committee

Spicer, Dr James james.spicer**[ta]**.ac.uk

Pre-clinical efcacy and safety evaluation of MOv18 IgE, a novel class of antibody targeting alpha folate receptor for CRUKD/14/001 a Phase I frst in class clinical trial.King's College London 01/06/2012 31/10/2015 New Agents Committee - DD Grant Application New Agents Committee

Preclinical development & CRUKD/14/001 A Cancer Research UK Phase I trial of MOv18, a frst in class chimaeric IgE antibody against folate receptor-alpha, in patients with advanced solid tumours including ovarian, colorectal & mesothelioma King's College London 01/10/2008 30/11/2017 New Agents Committee - DD Project Proposal New Agents Committee

Spiro, Professor Stephen stephenspiro**[ta]**nternet.com LungSearch Follow up - A randomised controlled trial of surveillance for the early detection of lung cancer in an at risk Group

University College London 01/10/2013 30/06/2016 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Starling, Dr Naureen naureen.starling**[ta]**.nhs.uk

CRUKE/ 15/ 015: A randomised, double-blind, placebo controlled, multi-centre phase II study to assess the efcacy and safety of 2nd line olaparib in combination with paclitaxel, in Western patients with advanced gastric and gastro-oesophageal junction (GOJ) cancer (OPERa) Royal Marsden NHS Foundation Trust 01/09/2015 31/08/2019 Clinical Trials Awards & Advisory Committee - Endorsement - Feasibility Study Clinical Trials Awards & Advisory Committee

Stenning, Professor Sally sally.stenning**[ta]**.ac.uk

Prospective evaluation and refnement of a targeted on-site monitoring strategy for multi-centre cancer clinical trials University College London 01/05/2012 30/04/2016 Population Research Committee - Project Award Population Research Committee

Steven, Dr Neil n.m.steven**[ta]**m.ac.uk

Grant support for CRUKD/13/001 Phase IB & Phase II trials to determine the immunogenicity & tolerability of extended schedule vaccination with MVA-EBV vaccine in patients with EBV+ nasopharyngeal carcinoma University of Birmingham 01/01/2012 31/12/2015 New Agents Committee - DD Grant Application New Agents Committee

CRUKD/13/001: A Cancer Research UK Phase Ib trial to determine the immunogenicity and tolerability of extended schedule vaccination with MVA-EBNA1/ LMP2 in patients with Epstein Barr Virus (EBV) positive malignancies University of Birmingham 01/04/2010 31/08/2018 New Agents Committee - DD Project Proposal New Agents CommitteeCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.Stewart, Dr Catherine catherine.stewart**[ta]**sgow.ac.uk

NEETs (Not in Education, Employment or Training) in Need University of Glasgow 01/10/2014 31/10/2015 Population Research Committee - BUPA Foundation Fund - Innovation Grant Population Research Committee

Stewart, Professor Grant g.s.stewart**[ta]**m.ac.uk

Understanding the control of cellular DNA damage responses and how defects in these pathways contribute to human disease University of Birmingham 01/09/2011 31/08/2017 New Investigator Committee - Senior Cancer Research Fellowship New Investigator Committee

Stratford, Professor Ian ian.stratford**[ta]**chester.ac.uk

Preclinical combination studies with MCT1 inhibitor AZD3965 and radiation University of Manchester 01/02/2014 31/07/2016 New Agents Committee - PreClinical Grants New Agents Committee

Strauss, Dr Sandra s.strauss**[ta]**.ac.uk

CRUKDE/14/021 ESPRIT: ESP1/SARC025 Global Collaboration: A Phase I study of a combination of the PARP inhibitor Niraparib and Temozolomide in patients with previously treated incurable Ewing's Sarcoma University College London Hospitals NHS Foundation Trust 01/07/2014 30/06/2016 New Agents Committee - Trial Grant Application New Agents Committee

Surrey, Dr Thomas thomas.surrey**[ta]**ck.ac.uk

Microtubule Cytoskeleton Laboratory The Francis Crick Institute 01/01/2011 31/12/2015 Biological Sciences Committee - Institute Group Award Science Committee

Svejstrup, Dr Jesper Mechanism of Gene Transcription Laboratory The Francis Crick Institute 01/11/2010 31/10/2015 Biological Sciences Committee - Institute Group Award Science Committee

Swanton, Professor Charles Translational Cancer Therapeutics The Francis Crick Institute 01/08/2013 31/07/2018 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

CRUK/14/020: Tracking Cancer Evolution through Therapy (Tracer X) University College London 01/01/2014 28/02/2023 Scientifc Executive Board - Programme Award Scientifc Executive Board

Talbot, Dr Denis denis.talbot**[ta]**ology.ox.ac.uk

CRUKD/11/001 VANSEL1: A Phase I dose escalation trial of the oral VEGF/EGFR inhibitor, Vandetanib (ZD6474) in combination with the oral MEK inhibitor Selumetinib (AZD6244)in patients with NSCLC University of Oxford 01/04/2010 31/01/2018 New Agents Committee - DD Project Proposal New Agents Committee

Tapon, Dr Nic Tissue size control in development and adult homeostasis The Francis Crick Institute 01/06/2013 31/05/2018 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Tarsounas, Dr Madalena Telomere and Genome Stability Group Cancer Research UK/ MRC Oxford Institute for Radiation Oncology 01/12/2011 30/11/2016 Biological Sciences Committee - Institute Group Award Science Committee

Tavaré, Professor Jeremy Investigations into the role of glycogen synthase kinase-3 in non small cell lung carcinoma.University of Bristol 01/07/2012 30/09/2015 Biological Sciences Committee - Project Award Science Committee

Tavaré, Professor Simon simon.tavare**[ta]**k.cam.ac.uk

Cancer Research UK Cambridge Institute Core Grant University of Cambridge 01/04/2013 31/03/2018 Scientifc Executive Board - Institute Grant Funded Core Award Scientifc Executive BoardCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.Taylor, Professor A.Malcolm a.m.r.taylor**[ta]**m.ac.uk

Variations in human syndromes with DNA damage response (DDR) defects: implications for new roles of DDR proteins, patient screening and discovery of new cancer syndromes University of Birmingham 01/01/2013 31/12/2015 Science Committee - Programme Award Science Committee

Taylor, Professor Stephen stephen.taylor**[ta]**chester.ac.uk

Exploiting mitosis towards designing novel anti-cancer strategies University of Manchester 01/05/2010 31/10/2016 New Investigator Committee - Senior Cancer Research Fellowship New Investigator Committee

Teichmann, Dr Sarah saraht**[ta]**.ac.uk

Immune cell-mediated steroidogenesis: a novel mechanism contributing to immune suppression within the tumour microenvironment European Molecular Biology Laboratory 01/07/2015 30/06/2018 Science Committee - Cancer Immunology Project Award Science Committee

Thirlwell, Dr Christina Identifcation of tumourigenic pathways and hypoxia induced epigenetic changes in the development of Neuroendocrine Tumours University College London 01/10/2010 31/12/2015 Clinical Careers Committee - Clinician Scientist Fellowship Clinical Careers Committee

Thomas, Professor Anne At107**[ta]**ac.uk

CRUKD/12/007: DEBIOC a Phase I dose-escalating study of EGFR inhibitor AZD8931 in combination with oxaliplatin and capecitabine chemotherapy in patients with oesophago-gastric adenocarcinoma University of Oxford 01/03/2012 31/10/2016 New Agents Committee - Trial Grant Application New Agents Committee

Thompson, Professor Alastair CRUK/07/018: MINDACT: (EORTC) A prospective, randomised study comparing the 70-gene signature with the common clinical-pathological criteria in selecting patients for adjuvant chemotherapy in nodenegative breast cancer University of Dundee 01/10/2007 31/03/2018 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Thompson, Dr Barry barry.thompson**[ta]**ck.ac.uk

Epithelial Biology Laboratory The Francis Crick Institute 01/07/2013 30/06/2018 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Tidy, Mr John john.tidy**[ta]**.nhs.uk

CRUK/13/015: A randomised phase III trial comparing radical hysterectomy and pelvic node dissection vs simple hysterectomy and pelvic node dissection in patients with low-risk early-stage certical cancer: The SHAPE trial (NCIC CTG Study CX.5) University College London 01/01/2015 31/12/2022 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Toda, Dr Takashi takashi.toda**[ta]**ck.ac.uk

Exploring the molecular mechanisms of mitotic spindle formation and organisation: nucleation and anchoring at the centrosome and dynamics at the spindlekinetochore interface The Francis Crick Institute 01/10/2012 30/09/2017 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Tomita, Dr Kazunori k.tomita**[ta]**.ac.uk

Identifcation of molecular link between telomeres and telomerase and investigation of the mechanism underlying telomerase recruitment and activation University College London 01/12/2010 30/11/2016 New Investigator Committee - Career Development Fellowship New Investigator CommitteeCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.Tomlinson, Professor Ian ian.tomlinson**[ta]**l.ox.ac.uk

Characterisation of the genetic causes of colorectal cancer University of Oxford 01/10/2013 30/09/2018 Science Committee - Programme Award Science Committee

Tooze, Dr Reuben r.tooze**[ta]**ds.ac.uk

Plasma cell quiescence and the origins of myeloma University of Leeds 01/01/2015 31/12/2019 Science Committee - Programme Award Science Committee

Tooze, Dr Sharon sharon.tooze**[ta]**ck.ac.uk

Molecular mechanisms of mammalian autophagy The Francis Crick Institute 01/03/2012 28/02/2017 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Treasure, Professor Tom CRUK/14/037 Pulmonary metastasectomy in colorectal cancer (PulMiCC): A Randomised trial of Pulmonary Metastasectomy in Colorectal Cancer University College London 01/04/2015 31/03/2020 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Treisman, Dr Richard Richard.Treisman**[ta]**ck.ac.uk

Mechanisms and biology of the SRF network and Rhoactin signalling The Francis Crick Institute 01/11/2012 31/10/2017 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Tristram, Dr Amanda Tristramaj**[ta]**ac.uk

CRUK/06/024: RT3 VIN: A randomised phase II multicentre trial of topical treatment in women with vulval intraepithelial neoplasia Cardiff University 01/11/2006 31/05/2016 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee